A knowledge construction methodology to automate case-based learning using clinical documents

The case-based learning (CBL) approach has gained attention in medical education as an alternative to traditional learning methodology. However, current CBL systems do not facilitate and provide computer-based domain knowledge to medical students for solving real-world clinical cases during CBL practice. To automate CBL, clinical documents are beneficial for constructing domain knowledge. In the literature, most systems and methodologies require a knowledge engineer to construct machine-readable knowledge. Keeping in view these facts, we present a knowledge construction methodology (KCM-CD) to construct domain knowledge ontology (i.e., structured declarative knowledge) from unstructured text in a systematic way using artificial intelligence techniques, with minimum intervention from a knowledge engineer. To utilize the strength of humans and computers, and to realize the KCM-CD methodology, an interactive case-based learning system(iCBLS) was developed. Finally, the developed ontological model was evaluated to evaluate the quality of domain knowledge in terms of coherence measure. The results showed that the overall domain model has positive coherence values, indicating that all words in each branch of the domain ontology are correlated with each other and the quality of the developed model is acceptable.     

Crude Oil Production

Current data on crude oil, field/lease condensate, and natural gas liquids produced from NGL plants. Updated on a monthly basis.     

摇摆运动下多环路主冷却剂系统自然循环流量的稳定性分析

海洋核动力平台因其突出的安全性已成为当今核能领域热点研究问题之一，但在海洋等非惯性条件下会使一回路系统的热工特性发生变化。针对此问题，本文对几种典型的一回路系统在摇摆条件下的自然循环流量波动特性进行计算分析。分别建立典型的双环路、三环路、四环路的一回路系统模型布置方案，并同时考虑摇摆中心的位置，根据流体动量守恒方程，得到不同状态下一回路系统内的流量变化规律。对于单堆双环路系统，摇摆中心在船上/中/下部位置时，环路流量波动幅度分别为13.2%/11.2%/9.5%，堆芯流量波动幅度分别为0.9%/0.8%/0.6%；对于单堆三环路系统，摇摆中心在船下部时，环路流量和堆芯流量波动幅度分别为9.2%和0.8%；对于单堆四环路系统，摇摆中心在船下部时，布置方案1和方案2的环路流量波动幅度分别为9.5%和9.2%，堆芯流量波动幅度分别为0.9%和0.7%。计算结果表明：采用单堆双环路的设计布置方案是最有利于系统稳定性的。     

Natural Gas Production

Current data on natural gas production, as well as a breakdown of production by country. Updated on a monthly basis.     

5-Benzylidene-4-Oxazolidinones Are Synergistic with Antibiotics for the Treatment of Staphylococcus aureus Biofilms

The failure of frontline antibiotics in the clinic is one of the most serious threats to human health and requires a multitude of novel therapeutics and innovative approaches to treatment so as to curtail the growing crisis. In addition to traditional resistance mechanisms resulting in the lack of efficacy of many antibiotics, most chronic and recurring infections are further made tolerant to antibiotic action by the presence of biofilms. Herein, we report an expanded set of 5-benzylidene-4-oxazolidinones that are able to inhibit the formation of Staphylococcus aureus biofilms, disperse preformed biofilms, and, in combination with common antibiotics, are able to significantly reduce the bacterial load in a robust collagen-matrix model of biofilm infection.     

管道清管器运行速度控制技术研究进展

随着对管道安全问题和降本增效理念的逐步重视，管道清管操作已成为全世界油气管道运行中必不可少的作业规程，清管器的运行速度是需要重点控制的参数之一，当其处于合理区间内时（原油管道1~5m/s，天然气管道2~7m/s），清管效果最佳。本文基于对管道清管数学模型的研究，首先论述了不同的被动控制方法，认为该方法较为灵活，应用广泛，对不同入口条件下清管器速度的准确计算是能否控制清管器速度处于合理区间的关键；然后对不同的主动控制方法进行了研究，研究表明：射流清管器速度控制的核心是旁通率的优选，其依赖于压降系数、皮碗与管壁间摩擦力的准确计算，建立简便可靠的摩擦力工程计算模型将有助于射流清管技术应用的进一步推广；最终本文对清管器智能调速技术进行综述和展望，指出发展稳定可靠的国产智能调速技术是未来重点研究方向。     

九里山矿中低压综合煤层注水应用与效果分析

为了降低九里山矿综采工作面煤尘质量浓度和瓦斯涌出量,根据九里山矿煤层特性,结合16051工作面的现场实际情况,在充分利用瓦斯抽采钻孔的基础上,探索出回风巷长孔低压渗透注水工艺,结合工作面短孔中压注水工艺,建立中、低压综合注水模式,并进行了分区域对比试验,考察了各区域的煤层含水率、煤尘质量浓度和瓦斯浓度。现场应用效果表明:中、低压综合注水效果较好,煤层含水率提高了2.94倍,煤尘质量浓度降低了80%以上,工作面瓦斯均匀释放,回风巷瓦斯浓度下降了30%以上,达到了较好的注水效果。     

Analysis of unsteady flow of blood conveying iron oxide nanoparticles on melting surface due to free convection using Casson model

Iron oxide nanoparticles have great importance in future biomedical applications because of their intrinsic properties, such as low toxicity, colloidal stability, and surface engineering capability. So, blood containing iron oxide nanoparticles are used in biomedical sciences as contrast agents following intravenous administration. The current problem deals with an analysis of the melting heat transfer of blood consisting iron nanoparticles in the existence of free convection. The principal equations of the problem are extremely nonlinear partial differential equations which transmute into a set of nonlinear ordinary differential equations by applying proper similarity transformations. The acquired similarity equalities are then solved numerically by Runge‐Kutta Felhsberg 45th‐order method. The results acquired are on the same level with past available results. Some noteworthy findings of the study are: the rate of heat transfer increases as the Casson parameter increases and also found that the temperature of the blood can be controlled by increasing or decreasing the Prandtl number. Hence, we conclude that flow and heat transfer of blood have significant clinical importance during the stages where the blood flow needs to be checked (surgery) and the heat transfer rate must be controlled (therapy).     

Constructal design of flat tubes cooled by natural convection

A set of vertical flat tubes cooled by natural convection and placed in a finite size space is designed based on the constructal law. The constraint in this design is the size of the space where the tubes are placed. The freedom inside the space is the distance between the tubes. When the constructal law is applied, the optimal distance between the tubes is determined. Rayleigh numbers are taken as (Ra = 10³, 10⁴, and 10⁵). The dimensionless tube diameter (tube diameter/tube height) is changed from (D* = 0.2) to (D* = 1) (circular tube). All the tubes are heated to the same wall temperature. The air used to cool the tubes has a Prandtl number (Pr = 0.72). The equations of conservation of mass, momentum, and energy for steady, two-dimensional, and incompressible flow are solved by the finite volume method. The result showed that the best or optimal distance at a given Rayleigh number remains constant for all tube diameters. The result also showed that the number of the small diameter tubes must be more than the number of the large-diameter tubes for the same Rayleigh number and the same size of the space to make the heat flow from the tubes to the coolant easier.